Diffusion MRI of

Traumatic Brain Injury

Diffusion MRI in Traumatic Brain Injury 2013

Workshop on Diffusion MRI in Traumatic Brain Injury: Software Tools and International Shared Data Repository, June 26 2013

Heidelberg, Germany

The workshop provided a platform for researchers from multiple disciplines to engage in a discussion on the challenges and potential of diffusion MRI software tools for evaluation of Traumatic Brain Injury (TBI). TBI is a major cause of death and disability globally and is considered a serious public health problem.

The international research community recognizes the importance of interdisciplinary collaboration to develop better diagnostic tools and treatments for traumatic brain injury (TBI). Informatics standardization of data elements and tools are sought together with the development of a shared data repository. An International Initiative for TBI Research (InTBIR) has been established and national efforts, such as the Federal Interagency Traumatic Brain Injury Research (FITBIR) informatics system in the USA, have been initiated.

The workshop includes presentations by experts with discussion of the challenges and opportunities by sponsors, computer scientists, biomedical engineers and medical physicists who develop and apply diffusion MRI software tools.

Meeting Program
Meeting Participants
CARS 2013 Workshop Program


Introduction

Michael Vannier, University of Chicago, Illinois (USA)
Heinz Lemke, CARS Foundation (Germany)

Presentation Slides (PDF, PPT)

Further Reading: Hitchhiker's guide to diffusion tensor MRI

 


TBI standards - common data elements
CENTER-TBI: comparative effectiveness research in TBI

Andrew I.R. Maas, Antwerp Univ. Hosp. (Belgium)

Presentation Slides (PDF, PPT)

Further Reading: IMPACT TBI NINDS CDE

 


Tools for the delineation of regional MR diffusion abnormalities in individual patients

Michael L. Lipton, Albert Einstein College of Medicine, New York (USA)

Presentation Slides (PDF, PPT)

Further Reading: AJNR Am J Neuroradiol, 2013 PLoS One, 2013 Brain Imaging Behav, 2012

 


Quantitative diffusion-tensor tractography can detect posttraumatic abnormalities that are not depicted at conventional MR

Nina Brandstack, Univ. of Turku (Finland)

Presentation Slides (PDF, PPT)

Further Reading: Radiology, April 2013 Ph. D. Dissertation

 


Quantitative tractography as a clinical diagnostic method in TBI

Timo Kurki, Univ of Turku (Finland)

Presentation Slides (PDF, PPT)

Further Reading: J Magn Reson Imaging., 2013 Clin Neuroradiol., 2011

 


Imaging biomarkers for early diagnosis of traumatic brain injury

Lyubomir Zagorchev, Philips Research, Briarcliff Manor, New York, (USA)

Presentation Slides (PDF, PPT)

Further Reading: Personal Webpage Imaging of Traumatic Brain Injury (PDF) Evaluation of TBI Patients using a shape-constrained deformable model, 2011 Manual Annotation, 3D Shape reconstruction and TBI analysis, 2011

 


Modeling brain injury and trajectory of brain changes from longitudinal multimodal imaging

Guido. Gerig, Univ. of Utah, Salt Lake City, Utah (USA)

Presentation Slides (PDF, PPT)

Further Reading: NAMIC TBI Project

 


DTI-STUDIO software for image processing

Susumu Mori, Johns Hopkins Univ. School of Medicine, Baltimore, Maryland (USA)

Presentation Slides (PDF, PPT)

Further Reading: DTI Studio

 


CAMINO and DTI-TK advanced diffusion MRI pipeline for traumatic brain injury

Gary Hui Zhang, Univ. College London (UK)

Presentation Slides (PDF, PPT)

Further Reading: Camino UCL Microstructure Imaging Group

 


MedInria neuroimaging software system and traumatic brain injury

Oliver Commowick, INRIA VISAGES, Rennes (France)

Presentation Slides (PDF, PPT)

Further Reading: MedInria

 


Federal Interagency Traumatic Brain Injury Research (FITBIR) informatics system – a Platform for International Collaboration

Ramona Hicks, NIH – National Institute of Neurological Disorders and Stroke, Bethesda, Maryland (USA)

Presentation Slides (PDF, PPT)

Further Reading: NINDS Trauma Program FITBIR

 


Federal Interagency Traumatic Brain Injury Research (FITBIR) Informatics System

Mathew McAuliffe, – NIH Center for Information Technology, Bethesda, Maryland (USA)

Presentation Slides (PDF, PPT)

Further Reading: FITBIR

 


ACR-Siemens traumatic brain injury workstation software environment

Benjamin Odry, Siemens Corporate Research, Princeton, New Jersey (USA)

Presentation Slides (PDF, PPT)

Further Reading: ACR – Siemens TBI Industry-government collaboration TATRC Software, TATRC Advances

 


Neuroimaging of structural pathology and connectomics in traumatic brain injury

Andrei Irimia, Univ. of California, Los Angeles, California (USA)

Presentation Slides (PDF, PPT)

Further Reading: Personal Website Laboratory of Neuro Imaging (LONI)

 


DTI image processing pipeline and cloud computing environment

Kyle Chard, Univ. of Chicago

Presentation Slides (PDF, PPT)

Further Reading:

Further Reading: Globus Online Globus Genomics

 

 


MITK – Medical Imaging Toolkit software for DTI processing

Klaus H. Maier‐Hein, German Cancer Research Center, Heidelberg (Germany)

Presentation Slides (PDF, PPT)

Further Reading: MITK

 


Panel Discussion – International cooperation on software tools development and testing using shared data repository – Moving the technology from the laboratory to the clinic